Normoxic polymer gel dosimetry using less toxic monomer of N-isopropyl acrylamide and X-ray computed tomography for radiation therapy applications
نویسندگان
چکیده
منابع مشابه
Impact of Photon Spectra on the Sensitivity of Polymer Gel Dosimetry by X-Ray Computed Tomography
Introduction: The purpose of the current study was to investigate the effect of X-ray spectra on the sensitivity of a polymer gel dosimeter imaged with a conventional computed tomography (CT) scanner. Material and Methods: The whole process of CT imaging of an irradiated polymer gel was simulated by MCNPX Monte Carlo (MC) code. The imaging of polyacrylamide gel was accomplished by means of a co...
متن کاملOptical and NMR dose response of N-isopropylacrylamide normoxic polymer gel for radiation therapy dosimetry.
BACKGROUND Application of less toxic normoxic polymer gel of N-isopropyl acrylamide (NIPAM) for radiation therapy has been studied in recent years. AIM In the current study the optical and NMR properties of NIPAM were studied for radiation therapy dosimetry application. MATERIALS AND METHODS NIPAM normoxic polymer gel was prepared and irradiated by 9 MV photon beam of a medical linac. The o...
متن کاملPolymer gel dosimetry using x-ray computed tomography: a feasibility study.
A new three-dimensional dosimetry technique using x-ray computed tomography (CT) to analyse polymer gels is proposed. The CT imaging is sensitive to radiation-induced density changes that occur within irradiated polyacrylamide gel (PAG). In this preliminary study, a CT imaging protocol is developed to optimize CT images of PAG; the response of PAG CT number to dose (N(CT)-dose response) and the...
متن کاملAccuracy and reproducibility in x-ray computed tomography polymer gel dosimetry
This work assesses the overall reproducibility and accuracy of an x-ray computed tomography (CT) polymer gel dosimetry (PGD) system using a N-isopropylacrylamide (NIPAM) based polymer gel and investigated what effects the use of generic, inter-batch, and intra-batch gel calibration have on dosimetric and spatial accuracy. Overall excellent spatial and dosimetric accuracy was found with this sys...
متن کاملdesign and construction of an optical computed tomography scanner for polymer gel dosimetry application
polymer gel dosimeter is the only accurate three dimensional (3d) dosimeter that can measure the absorbed dose distribution in a perfect 3d setting. gel dosimetry by using optical computed tomography (oct) has been promoted by several researches. in the current study, we designed and constructed a prototype oct system for gel dosimetry. first, the electrical system for optical scanning of the g...
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ژورنال
عنوان ژورنال: Reports of Practical Oncology & Radiotherapy
سال: 2010
ISSN: 1507-1367
DOI: 10.1016/j.rpor.2010.10.001